
| Title: | Novel Approach of Molecular Genetic Understanding of Iridology: Relationship Between Iris Constitution and Angiotensin Converting Enzyme Gene Polymorphism |
| DOI No: | doi:10.1142/S0192415X05003090 |
| Source: | The American Journal of Chinese Medicine, Vol. 33, No. 3 (2005) 501-505 |
| Copyright: | World Scientific Publishing Company & Institute for Advanced Research in Asian Science and Medicine |
| Author(s): | Jae-Young Um Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, South Korea Nyeon-Hyoung An College of Pharmacy, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Gui-Bi Yang Professional Graduate School of Oriental Medicine, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Geon-Mok Lee Professional Graduate School of Oriental Medicine, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Ju-Jang Cho Professional Graduate School of Oriental Medicine, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Jae-Woon Cho Professional Graduate School of Oriental Medicine, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Woo-Jun Hwang Professional Graduate School of Oriental Medicine, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Han-Jung Chae Department of Pharmacology and Cardiovascular Research Institute, School of Medicine, Chonbuk National University, South Korea Hyung-Ryong Kim Department of Dental Pharmacology and Nanoscience and Technology Research Institute, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Seung-Heon Hong College of Pharmacy, School of Dentistry, Wonkwang University, Iksan, Jeonbuk, 570-749, South Korea Hyung-Min Kim Correspondence to: Dr. Hyung-Min Kim, Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-701, Korea. Tel: file://C:/DOCUME~1/ADMINI~1/LOCALS~1/Temp/__SkypeIEToolbar_Cache/e70d958...)" skypeid="0" skypeaction="drop" skypesms="0"> (+82) 2-961-9448 Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, South Korea |
| Abstract: | Iridology is the study of the iris of the eye to detect the conditions of the body and its organs, genetic strengths and weaknesses, etc. Although iridology is not widely used as a scientific tool for healthcare professionals to get to the source of people's health conditions, it has been used as a supplementary source to help the diagnosis of medical conditions by noting irregularities of the pigmentation in the iris among some Korean Oriental medical doctors. Angiotensin converting enzyme (ACE) gene polymorphism is one of the most well studied genetic markers of vascular disease. We investigated the relationship between iridological constitution and ACE polymorphism in hypertensives. We classified 87 hypertensives and 79 controls according to iris constitution and determined the ACE genotype of each individual. DD genotype was more prevalent in patients with a neurogenic constitution than in controls. This finding supports the hypothesis that D allele is a candidate gene for hypertension and demonstrates the association among ACE genotype, Korean hypertensives and iris constitution. |
| Keywords: | Angiotensin Converting Enzyme (ACE); Gene; Polymorphism; Iris Constitution |
| References: | View references in HTML format (free for institutional subscribers) |
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| TOC: | Back to contents of Vol. 33, No. 3 |