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Clinical Neuro-Optic Reseach Initiative
  • Home
  • PupilMetrics Research
  • PupilMetrics Neuro
  • PupilCheck Beta
  • Register App
  • Learn More
    • PupilMetrics Research Academy
    • PupilMetrics Neuro Academy
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Getting Started

5
  • 1 System Requirements
  • 1.1 Installation
  • 1.2 Licensing
  • 1.3 First Launch
  • 1.4 Desktop Window & Keyboard Shortcuts

Capturing Eye Images

8
  • 2. Capturing Eye Images
  • 2.1 Camera Source Selection
  • 2.2 Quality-Gated Camera Mode – Android App
  • 2.3 Manual Camera Mode – Android
  • 2.4 USB / UVC Iriscope (Dino-Lite)
  • 2.5 PLR Video Mode – Android
  • 2.6 Import from Gallery
  • 2.7 Tips for a Good Capture

Reading the Analysis Results

13
  • 3. Reading the Analysis Results
  • 3.1 The Iris Zone Map
  • 3.2 PI Ratio (Pupil–Iris Ratio)
  • 3.3 Zone Findings — Flattenings (FLAT) and Protrusions (PROT)
  • 3.4 ANW Assessment (Collarette / Autonomic Nerve Wreath)
  • 3.5 Decentration (Pupil Position)
  • 3.6 Ellipseness (Pupil Shape)
  • 3.7 Anisocoria (Pupil Size Difference)
  • 3.8 Confidence Scores & Hybrid Fusion
  • 3.9 Scan History
  • 3.10 Visual Analysis Tools *(expanded)*
  • 3.11 Advanced Iris Research Toolkit
  • 3.12 PLR Signal Analysis Enhancements

Patient Management

4
  • 4. Patient Management & Exports
  • 4.1 PDF Report
  • 4.2 Plain-Text & JSON Export
  • 4.3 Sharing & Filing

Natural Medicine Therapy Panels

8
  • 5. Natural Medicine Therapy Panels
  • 5.1 Enabling the Therapy Modules
  • 5.2 How Zone Findings Drive the Therapy Panels
  • 5.3 Herbal Recommendations Panel
  • 5.4 Nutrition Recommendations Panel
  • 5.5 Chiropractic Correlations Panel
  • 5.6 TCM Correlations Panel
  • 5.7 Reading Therapy Panels Together

Constitutional Iridology

7
  • 6. Constitutional Iridology
  • 6.1 Background & Theoretical Basis
  • 6.2 The 34 Constitutional Types
  • 6.3 Selecting a Constitutional Type
  • 6.4 Constitutional Panel in Analysis Results
  • 6.5 Constitutional Section in the PDF Report
  • 6.6 Clinical Guidance & Limitations

Exporting PDF Reports

2
  • 7. Exporting PDF Reports
  • 7.1 Regenerating a PDF

Settings & Customization

7
  • 8. Settings & Customization
  • 8.1 Languages
  • 8.2 Zone Overlay & Observer Notes
  • 8.3 Zone Overlay & Observer Notes
  • 8.4 ML Comparison Panel
  • 8.5 About & Support
  • 8.6 Settings for the Advanced Research Toolkit

Clinical & Legal Disclaimers

3
  • 9. Clinical & Legal Disclaimers
  • 9.1 Data Privacy
  • 9.2 Research-Only Disclaimers for Advanced Features
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  • 8.2 Zone Overlay & Observer Notes

8.2 Zone Overlay & Observer Notes

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When **Show zone overlay** is on, the iris photo on the results screen displays an interactive polar overlay. Each clock-hour sector is tappable:

– Tap any zone to open its detail panel showing all FLAT/PROT/ANW findings in that zone, the associated organ system, and a text field for **observer notes**.

– Observer notes are free-form text written by the practitioner. They are included as a named section in both the TXT report and the PDF report under “Observer Notes / Zone Overlay”.

– Notes are session-local — they are not stored in the database between sessions.

Updated on March 24, 2026

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8.1 Languages8.3 Zone Overlay & Observer Notes

The Clinical Neuro-Optic Research Initiative (CNRI) advances pupil-based neurodiagnostics by preserving historical insights, developing modern analytic tools, and researching links between ocular microstructures and systemic health. Our mission is to validate and expand neuro-optic biomarkers for breakthroughs in early detection, monitoring, and non-invasive assessment of autonomic and neurological function.

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