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Clinical Neuro-Optic Reseach Initiative
  • Home
  • Human Eye Projects
    • The Pupil
    • Pupil Decentration-Multiformaties
    • Pupil Deformations
    • Pupil Color and Dimensions
    • Pupil Anisocoria
    • Pupil Miosis
    • Pupil Mydriasis
    • Pupil Reflexes
    • The Collarette
    • The Iris
  • PupilMetrics App
    • PupilMetrics Android
    • PupilMetrics Research Windows
    • PupilMetrics Research Mac OS
  • Documentation
  • Pricing
  • Learn More
    • PupilMetrics PDF Manual
    • CNRI Research
    • History
    • About
    • Eye Photo Tips & Tricks
    • IRB Status
    • Pupil Abstract Blog
    • Privacy Policy
    • Terms of Service
  • EyeShop
  • Cart

Getting Started

5
  • 1 System Requirements
  • 1.1 Installation
  • 1.2 Licensing
  • 1.3 First Launch
  • 1.4 Desktop Window & Keyboard Shortcuts

Capturing Eye Images

8
  • 2. Capturing Eye Images
  • 2.1 Camera Source Selection
  • 2.2 Quality-Gated Camera Mode – Android App
  • 2.3 Manual Camera Mode – Android
  • 2.4 USB / UVC Iriscope (Dino-Lite)
  • 2.5 PLR Video Mode – Android
  • 2.6 Import from Gallery
  • 2.7 Tips for a Good Capture

Reading the Analysis Results

13
  • 3. Reading the Analysis Results
  • 3.1 The Iris Zone Map
  • 3.2 PI Ratio (Pupil–Iris Ratio)
  • 3.3 Zone Findings — Flattenings (FLAT) and Protrusions (PROT)
  • 3.4 ANW Assessment (Collarette / Autonomic Nerve Wreath)
  • 3.5 Decentration (Pupil Position)
  • 3.6 Ellipseness (Pupil Shape)
  • 3.7 Anisocoria (Pupil Size Difference)
  • 3.8 Confidence Scores & Hybrid Fusion
  • 3.9 Scan History
  • 3.10 Visual Analysis Tools *(expanded)*
  • 3.11 Advanced Iris Research Toolkit
  • 3.12 PLR Signal Analysis Enhancements

Patient Management

4
  • 4. Patient Management & Exports
  • 4.1 PDF Report
  • 4.2 Plain-Text & JSON Export
  • 4.3 Sharing & Filing

Natural Medicine Therapy Panels

8
  • 5. Natural Medicine Therapy Panels
  • 5.1 Enabling the Therapy Modules
  • 5.2 How Zone Findings Drive the Therapy Panels
  • 5.3 Herbal Recommendations Panel
  • 5.4 Nutrition Recommendations Panel
  • 5.5 Chiropractic Correlations Panel
  • 5.6 TCM Correlations Panel
  • 5.7 Reading Therapy Panels Together

Constitutional Iridology

7
  • 6. Constitutional Iridology
  • 6.1 Background & Theoretical Basis
  • 6.2 The 34 Constitutional Types
  • 6.3 Selecting a Constitutional Type
  • 6.4 Constitutional Panel in Analysis Results
  • 6.5 Constitutional Section in the PDF Report
  • 6.6 Clinical Guidance & Limitations

Exporting PDF Reports

2
  • 7. Exporting PDF Reports
  • 7.1 Regenerating a PDF

Settings & Customization

7
  • 8. Settings & Customization
  • 8.1 Languages
  • 8.2 Zone Overlay & Observer Notes
  • 8.3 Zone Overlay & Observer Notes
  • 8.4 ML Comparison Panel
  • 8.5 About & Support
  • 8.6 Settings for the Advanced Research Toolkit

Clinical & Legal Disclaimers

3
  • 9. Clinical & Legal Disclaimers
  • 9.1 Data Privacy
  • 9.2 Research-Only Disclaimers for Advanced Features
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  • Home
  • PupilMetrics Documentation
  • Settings & Customization
  • 8.6 Settings for the Advanced Research Toolkit

8.6 Settings for the Advanced Research Toolkit

< 1 min read

All new tools are off by default. Each can be toggled independently from the settings menu.

| Setting | Default | Options | Effect |
|———|———|———|——–|
| **Gabor chip enabled** | On | On / Off | Adds/removes the Gabor chip on the Analysis Results screen |
| **Gabor scales** | 4 | 1 – 6 | Number of spatial frequencies in the Gabor bank |
| **Gabor orientations** | 8 | 4, 6, 8, 12 | Number of orientations in the Gabor bank |
| **LBP chip enabled** | On | On / Off | Adds/removes the LBP chip |
| **LBP radius** | 1 | 1, 2, 3 px | Neighbourhood radius for the LBP operator |
| **3D viewer — default palette** | Photo-texture | See §3.10.2E | Starting palette for the 3D relief viewer |
| **3D viewer — default mesh density** | Medium (128²) | Low · Medium · High · Ultra | Starting mesh resolution |
| **Inpainted image in overlays** | Off | On / Off | Use specular-inpainted image for all texture overlays |
| **Crypt detector enabled** | Off | On / Off | Auto-detect and report crypts in results & PDF |
| **Crypt detector minimum size** | 0.3 mm | 0.2 – 0.8 mm | Size threshold for reported crypts |
| **Contraction furrow detector** | Off | On / Off | Auto-detect nerve rings |
| **Iris signature recording** | Off | On / Off | Record iris signature for session verification |
| **Multi-frame fusion default** | Off | On / Off | Default capture mode sets multi-frame on |
| **PLR — extended analysis** | On | On / Off | Compute T75, hippus, and spectral analysis on PLR captures |

Updated on April 22, 2026

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8.5 About & Support8. Settings & Customization

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The Clinical Neuro-Optic Research Initiative (CNRI) advances pupil-based neurodiagnostics by preserving historical insights, developing modern analytic tools, and researching links between ocular microstructures and systemic health. Our mission is to validate and expand neuro-optic biomarkers for breakthroughs in early detection, monitoring, and non-invasive assessment of autonomic and neurological function.

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