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Clinical Neuro-Optic Reseach Initiative
  • Home
  • Human Eye Projects
    • The Pupil
    • Pupil Decentration-Multiformaties
    • Pupil Deformations
    • Pupil Color and Dimensions
    • Pupil Anisocoria
    • Pupil Miosis
    • Pupil Mydriasis
    • Pupil Reflexes
    • The Collarette
    • The Iris
  • PupilMetrics App
    • PupilMetrics Android
    • PupilMetrics Research Windows
    • PupilMetrics Research Mac OS
  • Documentation
  • Pricing
  • Learn More
    • CNRI Research
    • History
    • About
    • Eye Photo Tips & Tricks
    • IRB Status
    • Pupil Abstract Blog
    • Privacy Policy
    • Terms of Service
  • EyeShop
  • Cart

Getting Started

5
  • 1 System Requirements
  • 1.1 Installation
  • 1.2 Licensing
  • 1.3 First Launch
  • 1.4 Desktop Window & Keyboard Shortcuts

Capturing Eye Images

8
  • 2. Capturing Eye Images
  • 2.1 Camera Source Selection
  • 2.2 Quality-Gated Camera Mode – Android App
  • 2.3 Manual Camera Mode – Android
  • 2.4 USB / UVC Iriscope (Dino-Lite)
  • 2.5 PLR Video Mode – Android
  • 2.6 Import from Gallery
  • 2.7 Tips for a Good Capture

Reading the Analysis Results

10
  • 3. Reading the Analysis Results
  • 3.1 The Iris Zone Map
  • 3.2 PI Ratio (Pupil–Iris Ratio)
  • 3.3 Zone Findings — Flattenings (FLAT) and Protrusions (PROT)
  • 3.4 ANW Assessment (Collarette / Autonomic Nerve Wreath)
  • 3.5 Decentration (Pupil Position)
  • 3.6 Ellipseness (Pupil Shape)
  • 3.7 Anisocoria (Pupil Size Difference)
  • 3.8 Confidence Scores & Hybrid Fusion
  • 3.9 Scan History

Patient Management

4
  • 4. Patient Management & Exports
  • 4.1 PDF Report
  • 4.2 Plain-Text & JSON Export
  • 4.3 Sharing & Filing

Natural Medicine Therapy Panels

8
  • 5. Natural Medicine Therapy Panels
  • 5.1 Enabling the Therapy Modules
  • 5.2 How Zone Findings Drive the Therapy Panels
  • 5.3 Herbal Recommendations Panel
  • 5.4 Nutrition Recommendations Panel
  • 5.5 Chiropractic Correlations Panel
  • 5.6 TCM Correlations Panel
  • 5.7 Reading Therapy Panels Together

Constitutional Iridology

7
  • 6. Constitutional Iridology
  • 6.1 Background & Theoretical Basis
  • 6.2 The 34 Constitutional Types
  • 6.3 Selecting a Constitutional Type
  • 6.4 Constitutional Panel in Analysis Results
  • 6.5 Constitutional Section in the PDF Report
  • 6.6 Clinical Guidance & Limitations

Exporting PDF Reports

2
  • 7. Exporting PDF Reports
  • 7.1 Regenerating a PDF

Settings & Customization

6
  • 8. Settings & Customization
  • 8.1 Languages
  • 8.2 Zone Overlay & Observer Notes
  • 8.3 Zone Overlay & Observer Notes
  • 8.4 ML Comparison Panel
  • 8.5 About & Support

Clinical & Legal Disclaimers

2
  • 9. Clinical & Legal Disclaimers
  • 9.1 Data Privacy
View Categories
  • Home
  • PupilMetrics Documentation
  • Settings & Customization
  • 8.3 Zone Overlay & Observer Notes

8.3 Zone Overlay & Observer Notes

2 min read

When **Show zone overlay** is on, the iris photo on the results screen displays an interactive polar overlay. Each clock-hour sector is tappable:

– Tap any zone to open its detail panel showing all FLAT/PROT/ANW findings in that zone, the associated organ system, and a text field for **observer notes**.

– Each tapped zone is **automatically appended to the Observer Notes field** in the format `Zone Name — Organ System`. Tapping the same zone twice will not create a duplicate entry.

– Additional free-text commentary can be typed directly in the Observer Notes field alongside the auto-populated entries.

– Observer notes are included as a named section in both the TXT report and the PDF report under “Observer Notes / Zone Overlay”.

– Notes are session-local — they are not stored in the database between sessions.

#### Iris Sign Finder (Add Finding)

Below the Observer Notes field, an **Add Finding** panel allows the practitioner to record structured iris sign observations for the currently selected zone. This is based on the Bexel IRINA clinical classification system Government clinical trial approved studies of applying iridology and development of first approved medical device for the science of iridology and available to hospitals throughout the Asian Pacific rim.

**Workflow:**

1. Tap any zone on the polar overlay — the zone name and organ system are displayed and locked.

2. Tap the amber **Add Finding** header to expand the panel.

3. Select an **Anomaly type** from the dropdown. Organ-specific types appear at the top of the list automatically:

| Anomaly type | Notes |

|—|—|

| **Stroma change** | Structural fibre changes; select a subtype |

| **Organic pigment spot** | Pigmentation deposits; auto-generates clinical conclusion |

| **Slagging** | Microcirculation / connective tissue changes; auto-conclusion |

| **Toxic radii** | Radial sulci patterns; select a subtype |

| **Heterochromia** | Pigmentation variations; select a subtype |

| **Scurf rim** *(lung zones only)* | Local intoxication indicator; auto-conclusion |

| **Adaptive rings / arcs** *(lung zones only)* | Bronchospastic predisposition; auto-conclusion |

| **Autonomous wreath anomaly** *(cardiac zones only)* | ANW irregularity in cardiovascular zones |

4. If the selected type has **subtypes**, tap the appropriate chip (e.g. *Lacunae*, *Hyperemic sulci*, *Sectoral hyperpigmentation*).

5. Types with known clinical significance display an automatic **Conclusion** text drawn from the iridology reference database.

6. Tap **Add to Notes** — a structured entry is appended to the Observer Notes field in the format:

[Zone Name] Anomaly type › Subtype

  → Clinical conclusion text (if applicable)

Updated on April 2, 2026

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8.2 Zone Overlay & Observer Notes8.4 ML Comparison Panel

The Clinical Neuro-Optic Research Initiative (CNRI) advances pupil-based neurodiagnostics by preserving historical insights, developing modern analytic tools, and researching links between ocular microstructures and systemic health. Our mission is to validate and expand neuro-optic biomarkers for breakthroughs in early detection, monitoring, and non-invasive assessment of autonomic and neurological function.

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